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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C12orf45 All Species: 14.24
Human Site: S21 Identified Species: 44.76
UniProt: Q8N5I9 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5I9 NP_689531 188 20465 S21 S S P T R D S S G V P V S K E
Chimpanzee Pan troglodytes XP_001159986 185 20105 S21 S S P T R D S S G V P V S K E
Rhesus Macaque Macaca mulatta XP_001098582 185 20125 S21 L S P T R D S S R V P V S K E
Dog Lupus familis XP_531764 160 17872 W13 H L E N R G I W D R L L I Q P
Cat Felis silvestris
Mouse Mus musculus Q9CX66 185 19949 S21 S S S S V A C S Q V T V S R E
Rat Rattus norvegicus XP_001079678 186 20136 S21 S S S S V D C S R I T V S R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505739 298 31587 P151 P A P C P A G P G T P P A R D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782800 163 17924 Q16 N I G E K N I Q D S L L I K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 93 69.6 N.A. 70.7 71.8 N.A. 20.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 30.8
Protein Similarity: 100 98.4 94.1 76 N.A. 82.4 82.9 N.A. 35.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 48.4
P-Site Identity: 100 100 86.6 6.6 N.A. 46.6 46.6 N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 86.6 20 N.A. 60 66.6 N.A. 46.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 0 25 0 0 0 0 0 0 13 0 0 % A
% Cys: 0 0 0 13 0 0 25 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 50 0 0 25 0 0 0 0 0 13 % D
% Glu: 0 0 13 13 0 0 0 0 0 0 0 0 0 0 63 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 13 0 0 13 13 0 38 0 0 0 0 0 0 % G
% His: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 13 0 0 0 0 25 0 0 13 0 0 25 0 0 % I
% Lys: 0 0 0 0 13 0 0 0 0 0 0 0 0 50 13 % K
% Leu: 13 13 0 0 0 0 0 0 0 0 25 25 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 0 0 13 0 13 0 0 0 0 0 0 0 0 0 % N
% Pro: 13 0 50 0 13 0 0 13 0 0 50 13 0 0 13 % P
% Gln: 0 0 0 0 0 0 0 13 13 0 0 0 0 13 0 % Q
% Arg: 0 0 0 0 50 0 0 0 25 13 0 0 0 38 0 % R
% Ser: 50 63 25 25 0 0 38 63 0 13 0 0 63 0 0 % S
% Thr: 0 0 0 38 0 0 0 0 0 13 25 0 0 0 0 % T
% Val: 0 0 0 0 25 0 0 0 0 50 0 63 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _